Abstract

Point of care testing (POCT) refers to the analysis of samples by non laboratory staff at sites near to the patient. POCT has developed in an attempt to improve patient safety and care by providing immediate access to results of investigations. This allows prompt decision making about patient management and appropriate initiation or adjustment of treatment. The use of POCT is associated with improved time in the INR target range and a significant reduction in risk of thromboembolic events and death (SIGN 129 Antithrombotics: Indications and Management).

International Normalised ratio (INR) measurement for control of anticoagulation therapy with warfarin is an area where a number of analysers have been developed to perform the analysis. The majority of the analysers use a finger prick sample applied to a reagent strip that contains the reagent for analysis. The reaction is read on an analyser which measures the prothrombin time and calculates INR.